Value Proposition AAV has become one of the leading gene delivery vectors in clinical development. Gene therapy using recombinant AAV has been demonstrated to be safe and well-tolerated in virtually every clinical setting in which it has been used. To date nearly 100 clinical trials are testing the safety and efficacy of AAV based…

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Applications Optical based microscopes for use in clinical applications such as non-invasive imaging of human skin, eyes and hollow organs; research in drug discovery such as 3D visualization of drug kinetics in vivo; longitudinal monitoring therapeutic processes or biomedical research applications such as imaging cancer angiogenesis in mouse models in vivo. Patents Patents granted in…

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State-Of-Development:Initial testing has been completed, further optimization and scale-up is required. Abstract Background Gas sparging is a process by which gas is bubbled through a liquid medium. Typically, gas sparging is performed by transporting the gas through a tube comprising a plurality of nozzles; upon exiting the nozzles, the gas forms bubbles, which are subsequently…

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Rinses with sustained contact time and field coverage have been developed to prevent oral cancer. The Need Oral cancer affects nearly 50,000 Americans each year and has a five year survival rate of 57%. Often, oral cancer is only discovered when it has metastasized, as it does not present recognizable symptoms, and it has a…

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Effective screening during the toddler period may lead to timely detection of Autism Spectrum Disorder (ASD).  The Psychological Development Questionnaire-1 is a brief parent-report questionnaire designed to represent the expression of social attention, communication and reciprocity is young children and, inversely, to detect children at-risk for ASD. Details: Researchers at Rutgers University have created a…

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In modern medicine, an intubation procedure is performed on patients who are unconscious or who cannot breath on their own. An intubation procedure places a tube into the airway of the patient to allow ventilation of the lungs. Whether performed in the Emergency Medicine Department or in a controlled operating room, intubation can carry a…

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LAESI provides very precise in situ chemical analysis of biological samples using mass spectrometry (MS) technique. LAESI enables 2D and 3D imaging of metabolites, lipids, peptides and proteins in biological samples at the single cell level, empowering rapid chemical analyses in multiple fields of biology, medicine and chemistry. The LAESI device embodies an ionization source…

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Title: Veress Needle Interface for Tension Pneumothorax Decompression Invention: Inventors at the University of Arizona have designed an interface for the modified Veress needle (mVN) to address the shortcomings of older devices used to treat tension pneumothorax such as traditional needle thoracostomy (NT). This interface serves as an attachment that adds additional functionality to the standard Veress…

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Application:  This is a potential new product that has the potential to replace petroleum-based pressure sensitive adhesives with superior lignin derived components. Problems Addressed:  Creating pressure sensitive adhesives from materials that are derived directly from petroleum analogues is a process with numerous purification methods and polymerization steps. Polymerization is a process in which a chemical…

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New system leverages vehicle and roadside technologies to thwart head-on collisions caused by wrong-way drivers Researchers at UCF and the Central Florida Expressway Authority have designed and developed a comprehensive system that can help prevent head-on collisions by identifying and stopping drivers who wrongfully enter mainline highways. The inventive concept integrates existing transportation infrastructures and…

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